Clinical scenarios of unexplained sperm DNA fragmentation and their management
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منابع مشابه
P-7: Sperm DNA Assessment as A Tool for Partial Resolver of The Unexplained Infertility Problem
Background: To establish importance of sperm DNA assessment in resolving the unexplained infertility problem. Materials and Methods: This article is based on the careful observation of texts and papers from 2000-2014 about the DNA damage assessment as a significant parameter of sperm function test. Results: Acidic Aniline blue, Sperm Chromatin Dispersion test(SCD), Malondialdehyde concentration...
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tau.amegroups.com © Translational Andrology and Urology. All rights reserved. Approximately 15% of couples are unable to conceive after one year of unprotected intercourse and a male factor is solely responsible or contributory in approximately 50% (1). Of these couples up to 30% may have unexplained infertility with a normal semen analysis and no obvious reason for their inability to conceive ...
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tau.amegroups.com © Translational Andrology and Urology. All rights reserved. The expert panel made a tremendous effort to propose guidelines on the emerging trends of sperm DNA fragmentation testing and its clinical utility based on the available latest scientific evidence (1). Panel presented it in a systematic manner by a practical approach with four common clinical case scenarios. In the er...
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Background: Micronutrients in support to the carbon cycle were shown to reduce sperm DNA damage both in animal models and infertile men. Besides supporting DNA methylation, their positive effect may be mediated by an improved performance of the endogenous antioxidant system but this has not yet been proven in clinical settings. The present study aimed at evaluating the effects of micronutrient ...
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BACKGROUND/AIMS A large proportion of men with normal sperm results as analyzed using conventional techniques have fragmented DNA in their spermatozoa. We performed a prospective study to examine the incidence of DNA fragmentation in sperm in cases of couples with previously unexplained infertility and treated with intrauterine insemination. We evaluated whether there was any predictive value o...
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